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Article

Problems of oral anticoagulation in an adult with homozygous protein C deficiency and late onset of thrombosis.

Thrombosis and haemostasis - 1 Apr 1993

Pescatore P, Horellou H M, Conard J, Piffoux M, Van Dreden P, Ruskone-Fourmestraux A, Samama M

Abstract excerpt

We describe a 57-year-old woman with homozygous protein C deficiency and mild thrombotic manifestations consisting of three spontaneous distal deep vein thromboses occurring after the age of 45. Previous surgery and pregnancies had been uneventful. Low but detectable protein C antigen and activity levels (both 20%) were discovered on the occasion of skin necrosis induced by oral anticoagulation. This therapy was...

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Identifiers

PMID: 8497841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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