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Article

Is the maintainance of the C-terminus domain of dystrophin enough to ensure a milder Becker muscular dystrophy phenotype?

Human molecular genetics - 1 Jan 1993

Vainzof M, Takata R I, Passos-Bueno M R, Pavanello R C, Zatz M

Abstract excerpt

The severe Duchenne muscular dystrophy (DMD) and the more benign Becker type (BMD) are allelic conditions, controlled by a defective gene at Xp21, caused by the absence (DMD) or a defect in quantity or quality (BMD) of the protein dystrophin. It has been suggested that the C-terminus domain of dy...

Topics

Adolescent
Alleles
Blotting, Western
Child, Preschool
DNA
Dystrophin
Fluorescent Antibody Technique
Humans
Male
Muscles
Muscular Dystrophies
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Prognosis

Sequence Deletion

X Chromosome

Source

Identifiers

PMID: 8490621
DOI: 10.1093/hmg/2.1.39

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8490621-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Is the maintainance of the C-terminus domain of dystrophin enough to ensure a milder Becker muscular dystrophy phenotype?PMID 8490621Read ↗

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