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Article

Differentiation of Duchenne and Becker muscular dystrophy phenotypes with amino- and carboxy-terminal antisera specific for dystrophin.

American journal of human genetics - 1 Feb 1991

Bulman D E, Murphy E G, Zubrzycka-Gaarn E E, Worton R G, Ray P N

Abstract excerpt

Antibodies directed against the amino- and carboxy-terminal regions of dystrophin have been used to characterize 25 Duchenne muscular dystrophy (DMD), two intermediate, and two Becker muscular dystrophy (BMD) patients. Western blot analysis revealed an altered-size (truncated) immunoreactive dyst...

Topics

Adolescent
Blotting, Western
Child
Dystrophin
Electrophoresis, Polyacrylamide Gel
Humans
Immune Sera
Immunohistochemistry
Muscles
Muscular Dystrophies
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 1990838
PMCID: PMC1683012

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1990838-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Differentiation of Duchenne and Becker muscular dystrophy phenotypes with amino- and carboxy-terminal antisera specific for dystrophin.PMID 1990838Read ↗

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Is the carboxyl-terminus of dystrophin required for membrane association? A novel, severe case of Duchenne muscular dystrophy.Semantic proximity Read ↗

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