Article
A mutation in the dsbA gene coding for periplasmic disulfide oxidoreductase reduces transcription of the Escherichia coli ompF gene.
Molecular & general genetics : MGG - 1 Mar 1993
Pugsley A P
Abstract excerpt
An insertion mutation in the Escherichia coli dsbA gene, coding for periplasmic disulfide oxidoreductase, dramatically reduces the level of OmpF porin protein in the cell envelope. Studies with chromosomal ompF-lacZ operon and gene fusions indicate that this is due to reduced ompF transcription....
Topics
- Bacterial Outer Membrane Proteins
- Dithiothreitol
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Isomerases
- Mutation
- Protein Disulfide-Isomerases
- Transcription, Genetic