Article
The development of homologous (canine/anti-canine) antibodies in dogs with haemophilia A (factor VIII deficiency): a ten-year longitudinal study.
Thrombosis and haemostasis - 11 Jan 1993
Tinlin S, Webster S, Giles A R
Abstract excerpt
The development of inhibitors to factor VIII in patients with haemophilia A remains as a serious complication of replacement therapy. An apparently analogous condition has been described in a canine model of haemophilia A (Giles et al., Blood 1984; 63: 451). These animals and their relatives have...
Topics
- Animals
- Antibody Formation
- Disease Models, Animal
- Dog Diseases
- Dogs
- Factor VIII
- Hemophilia A
- Longitudinal Studies
- Pedigree
- Phenotype