Article
bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo.
Cell - 22 Oct 1993
Schejter E D, Wieschaus E
Abstract excerpt
A dynamic network of cortical microfilaments is associated with the cleavage furrow membranes during cellularization of the Drosophila embryo. A specific set of structural rearrangements in this network is required for orchestration and execution of its mechanistic roles. We describe the characterization of the gene bottleneck (bnk), mutations in which disturb the proper sequence of rearrangements of the...
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