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Article

Phenotypic and clonal analysis of T lymphocytes in childhood immune thrombocytopenic purpura

1 Oct 1993

Abstract excerpt

In an attempt to identify and characterize T-lymphocyte immunoregulatory abnormalities in immune thrombocytopenic purpura (ITP), we have performed phenotypic and clonal analysis on peripheral T lymphocytes from 23 children with ITP. Quantitation of lymphocyte subpopulations showed that children with acute ITP had higher numbers of CD45RA+ and lower numbers of CD45RO+ T cells than children with chronic ITP or...

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PMID: 8400263
DOI: 10.1182/blood.v82.7.2137.2137

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