Article
Viral interleukin 10 is critical for the induction of B cell growth transformation by Epstein-Barr virus.
1 Aug 1993
Abstract excerpt
We have used an efficient cDNA subtraction library procedure to identify newly induced genes in human B lymphocytes infected for 6 h with Epstein-Barr virus (EBV). Among the genes identified by automated sequencing of a random subset of clones from this library, one coded the EBV BCRF1 open reading frame, which specifies the viral interleukin 10 gene (vIL-10). This molecule is highly homologous to human (h)IL-10...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
