Article
L-myc proto-oncogene alleles and susceptibility to hepatocellular carcinoma.
International journal of cancer - 30 Jul 1993
Taylor J A, Bell D A, Nagorney D
Abstract excerpt
A common inherited RFLP of the L-myc proto-oncogene has been reported to correlate with cancer susceptibility or prognosis for some tumors. Using a PCR-based RFLP assay on DNA extracted from peripheral blood samples, we determined the L-myc EcoRI genotype of patients with HCC, patients with other liver tumors, and healthy controls. In this polymorphism there are 2 alleles, L and S, which define 3 possible...
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