Article
Expression of mutated epidermal growth factor receptor by non-small cell lung carcinomas.
Cancer research - 15 Jul 1993
Garcia de Palazzo I E, Adams G P, Sundareshan P, Wong A J, Testa J R, Bigner D D, Weiner L M
Abstract excerpt
The development of novel immunotherapy strategies for non-small cell lung cancer (NSCLC) will be facilitated by the identification of tumor-specific targets. Although the epidermal growth factor receptor (EGFR) is overexpressed in many cases of NSCLC, its wide distribution in normal tissue may li...
Topics
- Adenocarcinoma
- Amino Acid Sequence
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- ErbB Receptors
- Gene Deletion
- Humans
- Immunohistochemistry
- Karyotyping
- Lung Neoplasms
- Molecular Sequence Data
- Mutation