Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of mutated epidermal growth factor receptor by non-small cell lung carcinomas.

Cancer research - 15 Jul 1993

Garcia de Palazzo I E, Adams G P, Sundareshan P, Wong A J, Testa J R, Bigner D D, Weiner L M

Abstract excerpt

The development of novel immunotherapy strategies for non-small cell lung cancer (NSCLC) will be facilitated by the identification of tumor-specific targets. Although the epidermal growth factor receptor (EGFR) is overexpressed in many cases of NSCLC, its wide distribution in normal tissue may limit its suitability as an immunotherapeutic target. However, mutations within the EGFR that are unique to malignancies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Amino Acid Sequence
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Karyotyping

Share to Lung Neoplasms

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 8391918

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Expression of mutated epidermal growth factor receptor by non-small cell lung carcinomas.PMID 8391918Read ↗

Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors.Semantic proximity Read ↗

Epidermal growth factor receptor expression status in lung cancer correlates with its mutation.Semantic proximity Read ↗

Clinico-pathological and biological significance of tyrosine kinase domain gene mutations and overexpression of epidermal growth factor receptor for lung adenocarcinoma.Semantic proximity Read ↗

Immunohistochemical detection of mutated epidermal growth factor receptors in pulmonary adenocarcinoma.Semantic proximity Read ↗

Epidermal growth factor receptor mutation type III transfected into a small cell lung cancer cell line is predominantly localized at the cell surface and enhances the malignant phenotype.Semantic proximity Read ↗

High predictive value of epidermal growth factor receptor phosphorylation but not of EGFRvIII mutation in resected stage I non-small cell lung cancer (NSCLC).Semantic proximity Read ↗

Significance of EGFR Protein Expression and Gene Amplification in Non–Small Cell Lung CarcinomaSemantic proximity Read ↗

Profile of differentially expressed genes mediated by the type III epidermal growth factor receptor mutation expressed in a small-cell lung cancer cell line.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.