Article
Association of the antibodies against human papillomavirus 16 E4 and E7 proteins with cervical cancer positive for human papillomavirus DNA.
International journal of cancer - 19 Jun 1993
Onda T, Kanda T, Zanma S, Yasugi T, Watanabe S, Kawana T, Ueda K, Yoshikawa H, Taketani Y, Yoshiike K
Abstract excerpt
Occurrence of the antibodies against human papillomavirus (HPV) 16 proteins E4 and E7 is specifically but independently associated with cervical cancer. To correlate HPV DNA and antibody data, we examined the biopsy specimens and sera, by polymerase chain reaction (PCR) and by ELISA, respectively, from 51 patients with cervical cancer (including 3 recurrent cases) and 22 with cervical intra-epithelial neoplasia....
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