Article
Ubiquitous presence of E6 and E7 transcripts in human papillomavirus?Positive cervical carcinomas regardless of its type
1 Jan 2000
Abstract excerpt
The presence of human papillomavirus (HPV) DNA in almost all of the cervical carcinomas is one of the most compelling evidence for the viral carcinogenesis. HPVs are thought to induce cervical carcinoma most likely through the expression of E6 and E7 genes presumably by inactivating the tumor suppressor proteins, p53 and pRb, respectively. Thus far, the presence of HPV E6 and E7 transcripts have been identified...
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