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Article

Twin genes and endocrine disease: CYP21 and CYP11B genes.

Acta endocrinologica - 1 Aug 1993

Helmberg A

Abstract excerpt

CYP21 and CYP11B genes have a common feature: they are "twin" genes. It seems as if doubling and subsequent drifting apart rendered these genes particularly sensitive to defect acquisition by mechanisms involving recombinatorial events. This creates specific difficulties in the molecular diagnosis of defects.

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Share to Adrenal Hyperplasia, Congenital
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Steroid 11-beta-Hydroxylase

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Identifiers

PMID: 8372604
DOI: 10.1530/acta.0.1290097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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