Article
Analysis of delta-globin gene mutations in Greek cypriots.
Blood - 1 Sept 1993
Trifillis P, Kyrri A, Kalogirou E, Kokkofitou A, Ioannou P, Schwartz E, Surrey S
Abstract excerpt
We recently described four delta-globin gene mutations in Greek Cypriots studied by polymerase chain reaction (PCR) amplification and automated fluorescence-based DNA sequence analysis (Blood 78:3298, 1991). Selective restriction enzyme digestion of PCR products facilitated direct mutation detect...
Topics
- Base Sequence
- Cyprus
- Globins
- Greece
- Humans
- Molecular Sequence Data
- Mutation
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Prevalence
- Thalassemia