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Article

Global Analysis of Sequence Diversity within HIV-1 Subtypes across Geographic Regions

1 May 2012

Abstract excerpt

AIMS: HIV-1 sequence diversity can affect host immune responses and phenotypic characteristics such as antiretroviral drug resistance. Current HIV-1 sequence diversity classification uses phylogeny-based methods to identify subtypes and recombinants, which may overlook distinct subpopulations within subtypes. While local epidemic studies have characterized sequence-level clustering within subtypes using...

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PMID: 22822410
DOI: 10.2217/fvl.12.37

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