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Article

Differences of size and shape of active and inactive X‐chromosome domains in human amniotic fluid cell nuclei

1 May 1993

Abstract excerpt

Abstract It is a widely held belief that the inactive X‐chromosome (Xi) in female cell nuclei is strongly condensed as compared to the largely decondensed active X‐chromosome (Xa). We have reconsidered this problem and painted X‐chromosome domains in nuclei of subconfluent, female and male human amniotic fluid cell cultures (46, XX and 46, XY) by chromosomal in situ suppression (CISS) hybridization with...

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Share to Chromosomal and Genetic Variations
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Prenatal Screening and Diagnostics

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Identifiers

PMID: 8353309
DOI: 10.1002/jemt.1070250110

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