Article
Evidence of genetic heterogeneity in the autosomal recessive adult forms of limb-girdle muscular dystrophy following linkage analysis with 15q probes in Brazilian families.
Journal of medical genetics - 1 May 1993
Passos-Bueno M R, Richard I, Vainzof M, Fougerousse F, Weissenbach J, Broux O, Cohen D, Akiyama J, Marie S K, Carvalho A A
Abstract excerpt
The autosomal recessive limb-girdle muscular dystrophies (LGMD) represent a heterogeneous group of diseases which may be characterised by one or more autosomal loci. A gene at 15q has recently been found to be responsible for a mild form of LGMD in a group of families from the isolated island of...
Topics
- Brazil
- Chromosomes, Human, Pair 15
- DNA
- DNA Probes
- Female
- Genetic Linkage
- Genotype
- Humans
- Lod Score
- Male
- Muscular Dystrophies
- Pedigree