Article
Müllerian Inhibiting Substance is Present in Embryonic Testes of Dogs with Persistent Müllerian Duct Syndrome1
1 Jun 1993
Abstract excerpt
Müllerian Inhibiting Substance (MIS) causes regression of the Müllerian ducts during a critical period in embryonic development in male mammals. In Persistent Müllerian Duct Syndrome (PMDS), an autosomal recessive trait in humans and dogs, the Müllerian ducts fail to regress in otherwise normal males. Previously we reported that PMDS-affected dogs produce bioactive testicular MIS postnatally. The purpose of the...
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