Article
A eutherian X-linked gene, PDHA1, is autosomal in marsupials: a model for the evolution of a second, testis-specific variant in eutherian mammals.
Genomics - 1 Dec 1993
Fitzgerald J, Wilcox S A, Graves J A, Dahl H H
Abstract excerpt
We report the cloning and mapping of a gene (PDHA) for the pyruvate dehydrogenase E1 alpha subunit in marsupials. In situ hybridization and Southern blot analysis show that PDHA is autosomal in marsupials, mapping to chromosome 3q in Sminthopsis macroura and 5p in Macropus eugenii. Since these lo...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- Genetic Variation
- Humans
- Introns
- Isoenzymes
- Macromolecular Substances
- Macropodidae
- Male
- Marsupialia
- Molecular Sequence Data
- Pyruvate Dehydrogenase Complex
- Species Specificity
- Testis
- X Chromosome