Article
Meiotic sex chromosome inactivation in the marsupial Monodelphis domestica.
Genesis (New York, N.Y. : 2000) - 1 Nov 2007
Hornecker Jacey L, Samollow Paul B, Robinson Edward S, Vandeberg John L, McCarrey John R
Abstract excerpt
In eutherian mammals, the X and Y chromosomes undergo meiotic sex chromosome inactivation (MSCI) during spermatogenesis in males. However, following fertilization, both the paternally (Xp) and maternally (Xm) inherited X chromosomes are active in the inner cell mass of the female blastocyst, and then random inactivation of one X chromosome occurs in each cell, leading to a mosaic pattern of X-chromosome activity...
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