Article
Development and characterization of recA mutants of Campylobacter jejuni for inclusion in attenuated vaccines.
Infection and immunity - 1 Feb 1994
Guerry P, Pope P M, Burr D H, Leifer J, Joseph S W, Bourgeois A L
Abstract excerpt
Isogenic recA mutants of Campylobacter jejuni have been constructed for evaluation of their usefulness in attenuated vaccines against this major worldwide cause of diarrhea. The recA+ gene of C. jejuni 81-176 was cloned by using degenerate primers to conserved regions of other RecA proteins in a...
Topics
- Amino Acid Sequence
- Animals
- Bacterial Vaccines
- Base Sequence
- Campylobacter Infections
- Campylobacter jejuni
- Cloning, Molecular
- DNA Primers
- DNA, Bacterial
- Escherichia coli
- Female
- Genes, Bacterial
- Humans
- Molecular Sequence Data
- Mutation
- Rabbits
- Rec A Recombinases
- Restriction Mapping