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Article

Development and characterization of recA mutants of Campylobacter jejuni for inclusion in attenuated vaccines.

Infection and immunity - 1 Feb 1994

Guerry P, Pope P M, Burr D H, Leifer J, Joseph S W, Bourgeois A L

Abstract excerpt

Isogenic recA mutants of Campylobacter jejuni have been constructed for evaluation of their usefulness in attenuated vaccines against this major worldwide cause of diarrhea. The recA+ gene of C. jejuni 81-176 was cloned by using degenerate primers to conserved regions of other RecA proteins in a PCR. The C. jejuni recA+ gene encodes a predicted protein with an M(r) of 37,012 with high sequence similarity to other...

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Identifiers

PMID: 8300203
DOI: 10.1128/iai.62.2.426-432.1994
PMCID: PMC186125

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Development and characterization of recA mutants of Campylobacter jejuni for inclusion in attenuated vaccines.PMID 8300203Read ↗

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