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Article

Nature and distribution of chromosomal intertwinings in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Feb 1994

Spell R M, Holm C

Abstract excerpt

To elucidate yeast chromosome structure and behavior, we examined the breakage of entangled chromosomes in DNA topoisomerase II mutants by hybridization to chromosomal DNA resolved by pulsed-field gel electrophoresis. Our study reveals that large and small chromosomes differ in the nature and dis...

Topics

Centromere
Chromosome Mapping
Chromosomes, Fungal
DNA Repair
DNA Topoisomerases, Type II
DNA, Fungal
Gamma Rays
Genotype
Models, Structural
Plasmids
Saccharomyces cerevisiae

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Identifiers

PMID: 8289822
DOI: 10.1128/mcb.14.2.1465-1476.1994
PMCID: PMC358502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8289822-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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