Article
A third locus for autosomal dominant cerebellar ataxia type I maps to chromosome 14q24.3-qter: evidence for the existence of a fourth locus.
American journal of human genetics - 1 Jan 1994
Stevanin G, Le Guern E, Ravisé N, Chneiweiss H, Dürr A, Cancel G, Vignal A, Boch A L, Ruberg M, Penet C
Abstract excerpt
The autosomal dominant cerebellar ataxias (ADCA) type I are a group of neurological disorders that are clinically and genetically heterogeneous. Two genes implicated in the disease, SCA1 (spinal cerebellar ataxia 1) and SCA2, are already localized. We have mapped a third locus to chromosome 14q24...
Topics
- Adult
- Age of Onset
- Cerebellar Ataxia
- Chromosome Mapping
- Chromosomes, Human, Pair 14
- Female
- Genes, Dominant
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Male
- Middle Aged
- Pedigree