Estimating selective advantage of two alleles in discrete time.

doi:10.1007/BF00168046

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Article

Estimating selective advantage of two alleles in discrete time.

Journal of mathematical biology - 1 Jan 1993

Yip P, Watson R

Abstract excerpt

A class of estimators for the selective advantage, s, in a Wright-Fisher model with two alleles, variable population size, and genic selection is derived via martingale theory. Explicit expressions are given for these estimators which only involve simple computation. The optimal estimate among th...

Topics

Alleles
Genotype
Mathematics
Models, Genetic
Population Density
Time

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