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Article

Overdominant alleles in a population of variable size.

Genetics - 1 Jun 1999

Slatkin M, Muirhead C A

Abstract excerpt

An approximate method is developed to predict the number of strongly overdominant alleles in a population of which the size varies with time. The approximation relies on the strong-selection weak-mutation (SSWM) method introduced by J. H. Gillespie and leads to a Markov chain model that describes the number of common alleles in the population. The parameters of the transition matrix of the Markov chain depend in...

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Identifiers

PMID: 10353917
DOI: 10.1093/genetics/152.2.775
PMCID: PMC1460632

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