Altered nucleosome spacing associated with Down syndrome.

doi:10.1007/BF00557329

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Article

Altered nucleosome spacing associated with Down syndrome.

Biochemical genetics - 1 Jun 1993

Kahmann N H, Rake A V

Abstract excerpt

Micrococcal nuclease digestions of human leukocytes were analyzed using gel electrophoresis. The relative size (or average number of nucleotides) of nucleosomes was determined. The mean nucleosome size of the normal 46 chromosome karyotype is 185 +/- 2 bp. There was no significant variation in nu...

Topics

Adolescent
Adult
Aged
Child
Child, Preschool
Down Syndrome
Female
Genetic Variation
Humans
Infant
Male
Middle Aged
Nucleosomes
Specimen Handling
Time Factors

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