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Article

Altered nucleosome spacing associated with Down syndrome.

Biochemical genetics - 1 Jun 1993

Kahmann N H, Rake A V

Abstract excerpt

Micrococcal nuclease digestions of human leukocytes were analyzed using gel electrophoresis. The relative size (or average number of nucleotides) of nucleosomes was determined. The mean nucleosome size of the normal 46 chromosome karyotype is 185 +/- 2 bp. There was no significant variation in nucleosome size within the normal population due to age, sex, or race. The mean nucleosome size of the Down syndrome...

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Identifiers

PMID: 8259923
DOI: 10.1007/BF00557329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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