Article
Pathological characteristics of mucopolysaccharidosis VI in the rat.
Journal of comparative pathology - 1 Aug 1993
Yoshida M, Ikadai H, Maekawa A, Takahashi M, Nagase S
Abstract excerpt
The histological and electron microscopical characteristics of the pathology of rats with arylsulphatase B-deficient mucopolysaccharidosis (mucopolysaccharidosis VI; MPS VI) were investigated. In affected animals, intracytoplasmic vacuoles were prominent in chondrocytes, the macrophage system, ca...
Topics
- Animals
- Bone and Bones
- Cardiovascular System
- Cartilage
- Chondro-4-Sulfatase
- Cornea
- Disease Models, Animal
- Female
- Kupffer Cells
- Lysosomes
- Macrophages
- Male
- Mucopolysaccharidosis VI
- Nervous System
- Organ Size
- Phenotype
- Rats
- Rats, Mutant Strains