[Determination of the isoelectric point of beta-lactamases isolated from 67 Klebsiella oxytoca strains and phenotype behaviour against eight beta-lactam antibiotics].

Article

[Determination of the isoelectric point of beta-lactamases isolated from 67 Klebsiella oxytoca strains and phenotype behaviour against eight beta-lactam antibiotics].

Pathologie-biologie - 1 Apr 1993

Chardon H, Pachetti C, Collet L, Bellon O, Lagier E

Abstract excerpt

Klebsiella oxytoca is naturally resistant to aminopenicillins and carboxypenicillins by production of a chromosomal beta-lactamase but susceptible to third generation cephalosporins. The third generation cephalosporins activity may be reduced by: overproduction of the chromosomally encoded beta-l...

Topics

Anti-Bacterial Agents
Humans
In Vitro Techniques
Isoelectric Focusing
Isoelectric Point
Klebsiella
Phenotype
beta-Lactamases
beta-Lactams

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