Article
Activity of the yeast MAP kinase homologue Slt2 is critically required for cell integrity at 37 degrees C.
Molecular & general genetics : MGG - 1 Oct 1993
Martín H, Arroyo J, Sánchez M, Molina M, Nombela C
Abstract excerpt
Deletion of the SLT2 gene of Saccharomyces cerevisiae, which codes for a homologue of MAP (mitogen-activated) protein kinases, causes an autolytic lethal phenotype in cells grown at 37 degrees C. The gene encodes domains characteristic of protein kinases, which include a lysine (at position 54) that lies 19 residues from a glycine-rich cluster, considered to be the putative ATP binding site. The ability of three...
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