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Article

Polymorphism in the multi-phosphorylation domain of the human neurofilament heavy-subunit-encoding gene.

Gene - 15 Oct 1993

Figlewicz D A, Rouleau G A, Krizus A, Julien J P

Abstract excerpt

The C-terminal region of the human neurofilament heavy subunit (NEFH) contains a unique functional domain consisting of 43 repeat motifs of the amino acids (aa) Lys-Ser-Pro (KSP) with either 3- or 5-aa spacers in between. Past studies have demonstrated that the serine in these KSP motifs can be phosphorylated, resulting in heavy phosphorylation of this domain. Recent studies provide strong evidence for a role of...

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Source

Identifiers

PMID: 8224877
DOI: 10.1016/0378-1119(93)90211-k

Genes

NEFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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