Article
The iron superoxide dismutase of Legionella pneumophila is essential for viability.
Journal of bacteriology - 1 Jun 1994
Sadosky A B, Wilson J W, Steinman H M, Shuman H A
Abstract excerpt
Legionella pneumophila, the causative agent of Legionnaires' disease, contains two superoxide dismutases (SODs), a cytoplasmic iron enzyme (FeSOD) and a periplasmic copper-zinc SOD. To study the role of the FeSOD in L. pneumophila, the cloned FeSOD gene (sodB) was inactivated with Tn903dIIlacZ, f...
Topics
- Aconitate Hydratase
- Alleles
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Cloning, Molecular
- Diploidy
- Drug Resistance, Microbial
- Genes, Bacterial
- Genes, Lethal
- Lac Operon
- Legionella pneumophila
- Molecular Sequence Data
- Mutagenesis, Insertional
- Open Reading Frames
- Paraquat
- Recombinant Fusion Proteins
- Sequence Analysis, DNA