Article
The iron superoxide dismutase of Legionella pneumophila is essential for viability.
Journal of bacteriology - 1 Jun 1994
Sadosky A B, Wilson J W, Steinman H M, Shuman H A
Abstract excerpt
Legionella pneumophila, the causative agent of Legionnaires' disease, contains two superoxide dismutases (SODs), a cytoplasmic iron enzyme (FeSOD) and a periplasmic copper-zinc SOD. To study the role of the FeSOD in L. pneumophila, the cloned FeSOD gene (sodB) was inactivated with Tn903dIIlacZ, forming a sodB::lacZ gene fusion. By using this fusion, expression of sodB was shown to be unaffected by a variety of...
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