Article
Mechanisms of the escape phase of myeloma.
Blood reviews - 1 Mar 1994
Joshua D E, Gibson J, Brown R D
Abstract excerpt
In multiple myeloma the duration of plateau is an important clinical and biological determinant of quality of life and survival. During plateau phase, the tumour is in an indolent state, as manifested by a low labelling index of plasma cells and other proliferative markers, e.g. the thymidine kinase level. The mechanism by which plasma cells escape from this indolent phase to a more aggressive phase of this...
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