Article
Genetic risk assessment and specific-locus mutations in the ad-3 region of Neurospora crassa.
Environmental health perspectives - 1 Jan 1994
de Serres F J
Abstract excerpt
Data from experiments on the induction of specific-locus mutations in model systems are used in genetic risk assessment to estimate potential adverse effects in the human population. In such assessments with radiation or chemical mutagens, the following information is required: a) spontaneous and induced forward-mutation frequencies, b) dose-response curves for the overall induction of specific-locus mutations,...
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