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Article

Detection of human papillomavirus type 16/18 DNA in cervicovaginal cells by fluorescence based in situ hybridization and automated image cytometry.

Cytometry - 1 Mar 1994

Siadat-Pajouh M, Periasamy A, Ayscue A H, Moscicki A B, Palefsky J M, Walton L, DeMars L R, Power J D, Herman B, Lockett S J

Abstract excerpt

Automatic fluorescence image cytometry (AFIC) is a fast, sensitive, and reliable approach for screening slide-based clinical specimens. In this study, we applied AFIC to identify cancer-associated human papillomavirus (HPV) genotypes 16 and 18 in individual cells of cervical smears using a sensitive fluorescence based in situ hybridization (FISH) assay. HPV sequences were labeled by FISH and the cells imaged...

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Identifiers

PMID: 8187584
DOI: 10.1002/cyto.990150310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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