Article
Detection of human papillomavirus type 16/18 DNA in cervicovaginal cells by fluorescence based in situ hybridization and automated image cytometry.
Cytometry - 1 Mar 1994
Siadat-Pajouh M, Periasamy A, Ayscue A H, Moscicki A B, Palefsky J M, Walton L, DeMars L R, Power J D, Herman B, Lockett S J
Abstract excerpt
Automatic fluorescence image cytometry (AFIC) is a fast, sensitive, and reliable approach for screening slide-based clinical specimens. In this study, we applied AFIC to identify cancer-associated human papillomavirus (HPV) genotypes 16 and 18 in individual cells of cervical smears using a sensit...
Topics
- Algorithms
- Cervix Uteri
- DNA Probes, HPV
- DNA, Viral
- Female
- Flow Cytometry
- Genotype
- Humans
- Image Processing, Computer-Assisted
- In Situ Hybridization, Fluorescence
- Papillomaviridae
- Tumor Cells, Cultured
- Uterine Cervical Neoplasms
- Vaginal Smears