Article
Six years' experience with rapid karyotyping in prenatal diagnosis: correlations between phenotype detected by ultrasound and fetal karyotype.
Prenatal diagnosis - 1 Feb 1994
Claussen U, Ulmer R, Beinder E, Voigt H J
Abstract excerpt
From September 1985 to March 1992, 804 amniotic fluid samples from 64 different diagnostic centres of the Federal Republic of Germany were sent to our laboratory exclusively for rapid karyotyping. The average time needed for notification of the analysed karyotype was 4.65 days when the 'pipette method' was used for chromosome harvesting and 5.97 days when the 'in situ' technique was used. The overall incidence of...
Topics
- Amniocentesis
- Chromosome Aberrations
- Congenital Abnormalities
- Down Syndrome
- Facial Bones
- Female
- Fetal Growth Retardation
- Humans
- Karyotyping
- Neural Tube Defects
- Oligohydramnios