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Article

Vaccination against rabies: construction and characterization of SAG2, a double avirulent derivative of SADBern.

Vaccine - 1 Mar 1994

Lafay F, Bénéjean J, Tuffereau C, Flamand A, Coulon P

Abstract excerpt

A double avirulent mutant was isolated from the SADBern strain of rabies virus by two successive selection steps using neutralizing anti-glycoprotein monoclonal antibodies. Both mutations affect the triplet coding for amino acid 333 of the glycoprotein. The resulting virus, called SAG2, has a glutamate coded by GAA in position 333 instead of an arginine. This new codon differs by two nucleotides from all the...

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PMID: 8178553
DOI: 10.1016/0264-410x(94)90095-7

Genes

GAA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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