Article
Oral immunization of foxes with avirulent rabies virus mutants.
Veterinary microbiology - 1 Jun 1990
Le Blois H, Tuffereau C, Blancou J, Artois M, Aubert A, Flamand A
Abstract excerpt
SAG1, a rabies virus strain bearing one mutation which abolishes virulence for adult animals, was constructed from the SADBern strain of rabies virus which has previously been used as live vaccine for oral immunization of foxes. SAG1 also bears an antigenic mutation which serves as an additional marker of the strain. Studies on mice and four species of wild rodents showed that SAG1 is totally avirulent whereas...
Topics
- Animals
- Antigens, Viral
- Foxes
- Mutation
- Rabies
- Rabies Vaccines
- Rabies virus
- Vaccination
- Virulence