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Article

Role of common genetic polymorphisms in the LDL receptor gene in affecting plasma cholesterol levels in the general population.

Arteriosclerosis and thrombosis : a journal of vascular biology - 1 May 1994

Ahn Y I, Kamboh M I, Aston C E, Ferrell R E, Hamman R F

Abstract excerpt

A large number of rare mutations in the low-density lipoprotein (LDL) receptor gene cause the autosomal dominant disorder familial hypercholesterolemia. In addition, a number of common DNA polymorphisms have been identified in the LDL receptor gene, but their significance in affecting plasma cholesterol levels in the general population has not been studied widely. We investigated the role of two common DNA...

Topics

Alleles
Apolipoproteins E
Base Sequence
Cholesterol
Female
Gene Frequency
Hispanic or Latino
Humans
Linkage Disequilibrium
Male
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Receptors, LDL

Source

Identifiers

PMID: 8172843
DOI: 10.1161/01.atv.14.5.663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8172843-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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