Article
Apolipoprotein A-IV genetic polymorphism and its impact on quantitative traits in normoglycemic and non-insulin-dependent diabetic Hispanics from the San Luis Valley, Colorado.
Human biology - 1 Aug 1992
Kamboh M I, Iyengar S, Aston C E, Hamman R F, Ferrell R E
Abstract excerpt
Apolipoprotein A-IV exhibits a common two-allele polymorphism in several human populations studied to date. Using isoelectric focusing and immunoblotting, we have analyzed plasmas from 188 non-insulin-dependent diabetic and 238 normoglycemic Hispanic individuals from the San Luis Valley, Colorado, to determine APOA4 genotype frequencies and to estimate the impact of the genotypes on quantitative traits. The...
Topics
- Adult
- Aged
- Apolipoproteins A
- Blood Glucose
- Colorado
- Diabetes Mellitus, Type 2
- Female
- Gene Frequency
- Genotype
- Hispanic or Latino
- Humans