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Article

The ototoxic effect of toluene and the influence of noise, acetyl salicylic acid, or genotype. A study in rats and mice.

Scandinavian audiology. Supplementum - 1 Jan 1993

Johnson A C

Abstract excerpt

Toluene is a widely used organic solvent causing loss of auditory sensitivity in rats and presumably in humans. Also, the hearing loss in humans occupationally exposed to noise has been reported to be aggravated by simultaneous exposure to solvents. The aim of the present investigation was to study the effects of toluene, alone or in combination with other factors, on auditory sensitivity. The influence of...

Topics

Analysis of Variance
Animals
Aspirin
Auditory Threshold
Genotype
Hearing Loss, Noise-Induced
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Otoacoustic Emissions, Spontaneous
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats, Sprague-Dawley

Regression Analysis

Toluene

Source

Identifiers

PMID: 8171264

Genes

ABR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8171264-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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