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Article

Parasite virulence and disease patterns in Plasmodium falciparum malaria.

26 Apr 1994

Abstract excerpt

Heterogeneity in parasite virulence is one of several factors that have been proposed to contribute to the wide spectrum of disease severity in Plasmodium falciparum malaria. We used observed age-structured patterns of disease to define a population structure of P. falciparum, where the latter contains several independently transmitted antigenic types or "strains" that each induce some degree of strain-specific...

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PMID: 8170975
DOI: 10.1073/pnas.91.9.3715

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