Article
Genotypic characterization of sequential Candida albicans isolates from fluconazole-treated neutropenic patients.
The Journal of infectious diseases - 1 May 1994
van Belkum A, Melchers W, de Pauw B E, Scherer S, Quint W, Meis J F
Abstract excerpt
A polymerase chain reaction (PCR)-mediated genotyping assay for Candida albicans has been developed. By amplification of genomic regions bordered by eukaryotic or prokaryotic repeat-like motifs, differences between C. albicans isolates can be determined. The resolution of this typing procedure is...
Topics
- Adult
- Base Sequence
- Candida albicans
- Candidiasis
- DNA, Fungal
- Electrophoresis, Gel, Pulsed-Field
- Fluconazole
- Genotype
- Humans
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Neutropenia
- Polymerase Chain Reaction
- Repetitive Sequences, Nucleic Acid
- Retrospective Studies