Activation of telomerase in a human tumor.

Abstract excerpt

Tumors owe their perverse growth potential to changes in the controls that normally restrain somatic cells. The nowfamiliar players in this drama include distorted genes for growth factors and their receptors, misdirected signaling molecules, and errant cell-cycle regulators. Through these alterations cells evade many of the growth constraints imposed by their environment. But are such uncontrolled cells licensed...

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