The H-NS protein modulates the activation of the ilvIH operon of Escherichia coli K12 by Lrp, the leucine regulatory protein.

doi:10.1007/BF00283429

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Article

The H-NS protein modulates the activation of the ilvIH operon of Escherichia coli K12 by Lrp, the leucine regulatory protein.

Molecular & general genetics : MGG - 1 Mar 1994

Levinthal M, Lejeune P, Danchin A

Abstract excerpt

The H-NS protein, the product of the hns gene, plays a central role in the cellular response of bacteria to environmental stresses such as modification of osmolarity and temperature. The leucine regulatory protein (Lrp) controls a wide array of operons both as an activator (e.g. ilvIH) and as a repressor. We demonstrate that H-NS can decrease the activity of Lrp in stationary phase and under conditions of high...

Topics

Alleles
Bacterial Outer Membrane Proteins
Bacterial Proteins
DNA-Binding Proteins
Escherichia coli
Escherichia coli Proteins
Gene Expression Regulation, Bacterial
Genes, Bacterial
Leucine-Responsive Regulatory Protein
Multigene Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Operon

Regulon

Transcription Factors

Transcription, Genetic

Transcriptional Activation

Water-Electrolyte Balance

Source

Open in PubMed

Identifiers

PMID: 8152423
DOI: 10.1007/BF00283429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8152423-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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