Article
Dysregulated expression of tumor necrosis factor in chronic fatigue syndrome: interrelations with cellular sources and patterns of soluble immune mediator expression.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jan 1994
Patarca R, Klimas N G, Lugtendorf S, Antoni M, Fletcher M A
Abstract excerpt
Among a group of 70 individuals who met the criteria established by the Centers for Disease Control and Prevention (Atlanta) for chronic fatigue syndrome (CFS), 12%-28% had serum levels exceeding 95% of control values for tumor necrosis factor (TNF) alpha, TNF-beta, interleukin (IL) 1 alpha, IL-2, soluble IL-2 receptor (sIL-2R), or neopterin; overall, 60% of patients had elevated levels of one or more of the nine...
Topics
- Adult
- Biomarkers
- Cytokines
- Fatigue Syndrome, Chronic
- Female
- Humans
- Immunity, Cellular
- Leukocytes, Mononuclear
- Lymphotoxin-alpha
- Male