Multiple non-melanoma skin cancer: evidence that different MHC genes are associated with different cancers.

doi:10.1159/000247107

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Article

Multiple non-melanoma skin cancer: evidence that different MHC genes are associated with different cancers.

Dermatology (Basel, Switzerland) - 1 Jan 1994

Czarnecki D, Tait B, Nicholson I, Lewis A

Abstract excerpt

HLA DR frequencies of patients with multiple non-melanoma skin cancers were analysed. There were significant differences in the frequencies of HLA DR1, DR4 and DR7 between patients who only had basal cell carcinomas and patients who had both basal and squamous cell carcinomas. There were significant differences in the frequency of HLA DR53 between the two groups. This antigen is in linkage disequilibrium with HLA...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Carcinoma, Basal Cell
Carcinoma, Squamous Cell
Female
Gene Frequency
HLA-DR Antigens
HLA-DR4 Antigen
HLA-DR7 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DRB4 Chains

Humans

Major Histocompatibility Complex

Male

Middle Aged

Neoplasms, Multiple Primary

Skin Neoplasms

Source

Open in PubMed

Identifiers

PMID: 8136554
DOI: 10.1159/000247107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8136554-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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