Article
The effects of fur on the transcriptional and post-transcriptional regulation of MnSOD gene (sodA) in Escherichia coli.
Archives of biochemistry and biophysics - 1 Mar 1994
Schrum L W, Hassan H M
Abstract excerpt
Earlier studies have shown that the Fur (ferric uptake regulation) protein acts as an anaerobic/aerobic repressor of MnSOD (sodA) expression. We found that the aerobic expression of sodA::lacZ fusion in a Fur- background to be threefold higher than in a Fur+ background. This effect of fur mutation was not seen in a strain harboring the sodA+ gene instead of the sodA::lacZ fusion. However, we observed a...
Topics
- Aerobiosis
- Bacterial Proteins
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Iron
- Manganese
- Mutation
- Plasmids
- RNA, Messenger
- Recombinant Fusion Proteins
- Repressor Proteins