Heterogeneity of severe dystrophic epidermolysis bullosa: overexpression of collagen VII by cutaneous cells from a patient with mutilating disease.

doi:10.1111/1523-1747.ep12371754

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Article

Heterogeneity of severe dystrophic epidermolysis bullosa: overexpression of collagen VII by cutaneous cells from a patient with mutilating disease.

The Journal of investigative dermatology - 1 Feb 1994

König A, Winberg J O, Gedde-Dahl T, Bruckner-Tuderman L

Abstract excerpt

Severe mutilating recessive dystrophic epidermolysis bullosa presents with extensive blistering, scarring, and pseudosyndactylies. The skin of most affected individuals lacks normal anchoring fibrils and contains no, or drastically reduced amounts of, collagen VII, the major fibril component. Her...

Topics

Adult
Antigens
Basement Membrane
Blotting, Northern
Blotting, Southern
Cell Adhesion Molecules
Cells, Cultured
Collagen
Epidermolysis Bullosa Dystrophica
Fluorescent Antibody Technique
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Laminin

Male

Metalloendopeptidases

Phenotype

RNA, Messenger

Skin

Kalinin

Source

Open in PubMed

Identifiers

PMID: 8106746
DOI: 10.1111/1523-1747.ep12371754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8106746-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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