Article
Double-strand DNA conformation polymorphisms as a source of highly polymorphic genetic markers.
Animal genetics - 1 Jun 1993
Kirkpatrick B W, Huff B M, Casas-Carrillo E
Abstract excerpt
The molecular basis for several apparent restriction fragment length polymorphisms of the porcine growth hormone gene was examined through DNA sequence analysis. Electrophoretic and sequence analysis suggest polymorphisms result from 1-3 base substitutions that affect double-strand DNA conformati...
Topics
- Alleles
- Animals
- Base Sequence
- DNA
- Electrophoresis, Polyacrylamide Gel
- Gene Frequency
- Genetic Linkage
- Genetic Markers
- Growth Hormone
- Haplotypes
- Molecular Sequence Data
- Nucleic Acid Conformation
- Pedigree
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Swine