Article
[The relation of polymorphism of low-density lipoprotein receptor gene with serum cholesterol levels].
Zhonghua yi xue za zhi - 1 Apr 1993
Fan L M
Abstract excerpt
PvuII polymorphism of LDL receptor gene and serum lipid levels were analysed in 115 normolipidemic subjects and 57 individuals with hypercholesterolemia. A significant relationship was found between P2 allele and lower serum cholesterol level, suggesting that the LDL receptor may contribute to the variation in cholesterol levels in normolipidemic population. Although the frequency of P2 allele in the Chinese was...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Cholesterol
- Female
- Genes
- Humans
- Hypercholesterolemia
- Male
- Polymorphism, Restriction Fragment Length
- Receptors, LDL
